Ki-67 is a protein found in cells that are actively dividing. It’s not found in resting cells. Neuroendocrine tumors with high amounts of Ki-67 are typically faster-growing cancers and more aggressive. This is called high Ki-67. A low Ki-67 means the tumor is slower growing.
A biopsy on solid tumor tissue will be sent for testing and results will indicate the percentage of cells that are multiplying. This is called the Ki-67 index and will be used to grade the tumor and plan treatment.
Neuroendocrine tumors with a low Ki-67 are more likely to use somatostatin analogs (SSAs), PRRT, and targeted therapies.
Ask your doctor how your biomarker test results are informing your treatment plan and if you qualify for any clinical trials.
